Pseudomonas aeruginosa PAO1, PA1624

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1624
Name
Replicon chromosome
Genomic location 1766956 - 1767762 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250315.1
GI 15596821
Affymetrix PA1624_at
DNASU PaCD00006743
Entrez 881888
GenBank AAG05013.1
INSDC AAG05013.1
NCBI Locus Tag PA1624
protein_id(GenBank) gb|AAG05013.1|AE004590_4|gnl|PseudoCAP|PA1624
TIGR NTL03PA01625
UniParc UPI00000C5413
UniProtKB Acc Q9I398
UniProtKB ID Q9I398_PSEAE
UniRef100 UniRef100_W0YNK9
UniRef50 UniRef50_W0YNK9
UniRef90 UniRef90_W0YNK9

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.85
Kyte-Doolittle Hydrophobicity Value -0.134
Molecular Weight (kDa) 29.5
Isoelectric Point (pI) 6.37

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6TD9 UNKNOWN FUNCTION 11/08/19 X-ray structure of mature PA1624 from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 1.96 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 17 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003747 (538 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1624

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
The hypothetical periplasmic protein PA1624 from Pseudomonas aeruginosa folds into a unique two-domain structure.
Feiler CG, Weiss MS, Blankenfeldt W
Acta Crystallogr F Struct Biol Commun 2020 Dec 1;76(Pt 12):609-615
PubMed ID: 33263573