Pseudomonas sp. MOIL14HWK12:I1, PSEK12I1_RS0122075
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas sp. MOIL14HWK12:I1
GCF_000510705.1|latest |
| Locus Tag |
PSEK12I1_RS0122075
|
| Name |
|
| Replicon | scaffold_4.5 |
| Genomic location | 208965 - 212102 (+ strand) |
Cross-References
| RefSeq | WP_027598429.1 |
| GI | 653585493 |
| NCBI Locus Tag | PSEK12I1_RS0122075 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
multidrug transporter
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -0.62 |
| Kyte-Doolittle Hydrophobicity Value | 0.285 |
| Molecular Weight (kDa) | 113.1 |
| Isoelectric Point (pI) | 6.88 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AMR gene predictions from CARD database
Identified using the Resistance Gene Identifier (RGI)
| Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
| adeF | AdeF is the membrane fusion protein of the multidrug efflux complex AdeFGH. [PMID:20696879] | ARO:3000777 | protein homolog model | Strict | 755.7 | 42.78 | 3.2.5 |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Drugs Targeting this Protein
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
| Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
| Deoxycholic Acid | DB03619 | DrugBank | 5.1.4 | P31224 | Multidrug efflux pump subunit AcrB | 66.8 | 1049 | 0.0e+00 |
| Rhodamine 6G | DB03825 | DrugBank | 5.1.4 | P31224 | Multidrug efflux pump subunit AcrB | 66.8 | 1049 | 0.0e+00 |
| Dequalinium | DB04209 | DrugBank | 5.1.4 | P31224 | Multidrug efflux pump subunit AcrB | 66.8 | 1049 | 0.0e+00 |
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000417 (2093 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PSEK12I1_RS0122075
Search term: multidrug transporter
|
Human Homologs
References
No references are associated with this feature.