Pseudomonas aeruginosa PA7, PSPA7_5556 (cntO)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PA7
GCF_000017205.1|latest |
| Locus Tag |
PSPA7_5556
|
| Name |
cntO
Synonym: TonB-dependent Outer Membrane Protein ZrmA Synonym: zrmA |
| Replicon | chromosome |
| Genomic location | 5719990 - 5722101 (- strand) |
| Comment | part of the Zur-regulated metallophore operon known as cntOLMI (PMID:29214991) or zrmABCD(PMID:28898501). |
Cross-References
| RefSeq | YP_001350877.1 |
| GI | 152987867 |
| Entrez | 5355570 |
| NCBI Locus Tag | PSPA7_5556 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
CntO
|
| Synonyms |
outer membrane protein |
| Evidence for Translation | |
| Charge (pH 7) | -14.90 |
| Kyte-Doolittle Hydrophobicity Value | -0.593 |
| Molecular Weight (kDa) | 78438.2 |
| Isoelectric Point (pI) | 5.44 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 300 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000149 (2669 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PSPA7_5556
Search term: cntO
Search term: CntO
|
Human Homologs
References
|
Growth of Pseudomonas aeruginosa in zinc poor environments is promoted by a nicotianamine-related metallophore.
Mastropasqua MC, D'Orazio M, Cerasi M, Pacello F, Gismondi A, Canini A, Canuti L, Consalvo A, Ciavardelli D, Chirullo B, Pasquali P, Battistoni A
Mol Microbiol 2017 Nov;106(4):543-561
PubMed ID: 28898501
|
|
Pseudomonas aeruginosa zinc uptake in chelating environment is primarily mediated by the metallophore pseudopaline.
Lhospice S, Gomez NO, Ouerdane L, Brutesco C, Ghssein G, Hajjar C, Liratni A, Wang S, Richaud P, Bleves S, Ball G, Borezée-Durant E, Lobinski R, Pignol D, Arnoux P, Voulhoux R
Sci Rep 2017 Dec 7;7(1):17132
PubMed ID: 29214991
|