Pseudomonas aeruginosa UCBPP-PA14, PA14_37590 (kynB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0019441 tryptophan catabolic process to kynurenine
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01969
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004061 arylformamidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.50.30.50
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004328 formamidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01969
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other UCBPP-PA14 genes in this class
Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00380 Tryptophan metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc quinoxaline-2-carboxylate biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc L-tryptophan degradation XI (mammalian, via kynurenine) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pau00630 Glyoxylate and dicarboxylate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP aerobic degradation of L-tryptophan (kynurenine pathway) ECO:0000037
not_recorded
MetaCyc 3-hydroxyquinaldate biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc 3-hydroxy-4-methyl-anthranilate biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc 3-hydroxy-4-methyl-anthranilate biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.50.30.50 Putative cyclase IPR037175 Kynurenine formamidase superfamily 1 213 2.1E-67
FunFam G3DSA:3.50.30.50:FF:000001 Kynurenine formamidase - - 3 209 7.1E-89
SUPERFAMILY SSF102198 Putative cyclase IPR037175 Kynurenine formamidase superfamily 4 207 1.83E-59
PANTHER PTHR31118 CYCLASE-LIKE PROTEIN 2 IPR007325 Kynurenine formamidase/cyclase-like 5 206 1.5E-24
Hamap MF_01969 Kynurenine formamidase [kynB]. IPR017484 Kynurenine formamidase, bacteria 5 209 45.113441
NCBIfam TIGR03035 JCVI: arylformamidase IPR017484 Kynurenine formamidase, bacteria 5 209 9.0E-104
Pfam PF04199 Putative cyclase IPR007325 Kynurenine formamidase/cyclase-like 8 152 1.1E-17

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.