Pseudomonas aeruginosa PAO1, PA4814 (fadH2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 2506179 Reviewed by curator
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07992
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0010181 FMN binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00724
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Fatty acid and phospholipid metabolism Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51395 FMN-linked oxidoreductases - - 11 372 2.22E-107
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 12 379 4.6E-119
FunFam G3DSA:3.20.20.70:FF:000082 NADPH-dependent 2,4-dienoyl-CoA reductase - - 12 379 0.0
PANTHER PTHR42917 2,4-DIENOYL-COA REDUCTASE - - 13 681 0.0
CDD cd02930 DCR_FMN - - 16 368 0.0
Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal 16 340 7.9E-75
SUPERFAMILY SSF51971 Nucleotide-binding domain - - 343 527 1.65E-40
Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase IPR023753 FAD/NAD(P)-binding domain 385 643 1.5E-20
Gene3D G3DSA:3.40.50.720 - - - 385 674 7.0E-111
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature - - 386 408 1.3E-5
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature - - 387 406 1.1E-11
SUPERFAMILY SSF51905 FAD/NAD(P)-binding domain IPR036188 FAD/NAD(P)-binding domain superfamily 479 636 5.44E-15
Gene3D G3DSA:3.50.50.60 - IPR036188 FAD/NAD(P)-binding domain superfamily 480 634 7.0E-111
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature - - 507 525 1.1E-11
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature - - 627 643 1.1E-11
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature - - 628 642 1.3E-5

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.