Pseudomonas aeruginosa PAO1, PA2586 (gacA)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0000156	phosphorelay response regulator activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	7604262	Reviewed by curator
Biological Process	GO:1900233	positive regulation of single-species biofilm formation on inanimate substrate	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	11401724	Reviewed by curator
Biological Process	GO:0006355	regulation of transcription, DNA-templated	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF46894	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0000160	phosphorelay signal transduction system	ISM Inferred from Sequence Model Term mapped from: InterPro:SM00448	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003677	DNA binding	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF46894	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae02025	Biofilm formation - Pseudomonas aeruginosa	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae02020	Two-component system	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	164	180	5.5E-5
Pfam	PF00072	Response regulator receiver domain	IPR001789	Signal transduction response regulator, receiver domain	4	116	2.5E-28
SMART	SM00448	REC_2	IPR001789	Signal transduction response regulator, receiver domain	2	115	6.8E-30
PANTHER	PTHR43214	TWO-COMPONENT RESPONSE REGULATOR	IPR039420	Transcriptional regulatory protein WalR-like	2	208	3.1E-50
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	180	192	5.5E-5
Gene3D	G3DSA:3.40.50.2300	-	-	-	2	210	8.2E-61
FunFam	G3DSA:3.40.50.2300:FF:000015	Two-component response regulator UvrY	-	-	2	210	3.5E-121
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	150	164	5.5E-5
SUPERFAMILY	SSF52172	CheY-like	IPR011006	CheY-like superfamily	1	132	3.27E-34
CDD	cd06170	LuxR_C_like	IPR000792	Transcription regulator LuxR, C-terminal	150	206	4.63353E-13
Pfam	PF00196	Bacterial regulatory proteins, luxR family	IPR000792	Transcription regulator LuxR, C-terminal	148	204	1.1E-14
SUPERFAMILY	SSF46894	C-terminal effector domain of the bipartite response regulators	IPR016032	Signal transduction response regulator, C-terminal effector	132	211	2.07E-18
SMART	SM00421	luxrmega5	IPR000792	Transcription regulator LuxR, C-terminal	147	204	4.4E-18
CDD	cd17535	REC_NarL-like	-	-	4	120	1.50022E-49

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.